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Is My Medication Temperature-Controlled?

Understanding cold-chain shipping and proper medication storage.

Updated over 2 months ago

Temperature-Sensitive Medications

Most injectable medications from Good Girl Rx require refrigeration and are shipped with temperature controls.

Medications requiring refrigeration (36°F to 46°F / 2°C to 8°C):

  • Compounded Semaglutide

  • Compounded Tirzepatide

  • NAD+ Injections

  • B12 Injections

  • Glutathione Injections

  • Lipotropic (MIC) + B12 Injections

  • Sermorelin Injections

  • Brand-name GLP-1s (Ozempic, Wegovy, Mounjaro, Zepbound)

Medications that do NOT require refrigeration:

  • NAD+ Face Cream (store at room temperature)

  • NAD+ Nasal Spray (varies — check included instructions)

  • Sermorelin Tablets (store at room temperature)


How Temperature-Controlled Shipping Works

Your medication is shipped in:

Insulated packaging: Specialized foam or reflective insulation that maintains temperature for 48-72+ hours under normal conditions.

Cold packs: Gel ice packs placed around the medication to maintain refrigeration temperatures during transit.

2-day air shipping: Expedited shipping minimizes time in transit, reducing temperature exposure risk.


What to Do When Your Package Arrives

1. Retrieve your package promptly Don't leave it outside in hot or cold weather longer than necessary.

2. Inspect the cold packs It is normal for cold packs to be partially or fully melted upon arrival. The insulation is designed to maintain temperature even as the packs thaw. Melted cold packs do NOT necessarily mean your medication is compromised.

3. Refrigerate your medication within 24 hours As long as you refrigerate promptly, your medication should be safe to use even if the cold packs have melted.

4. Inspect the medication Check for any visible issues:

  • Discoloration

  • Cloudiness in a solution that should be clear

  • Particles floating in the vial

  • Cracked or broken vials

  • Damaged seals or packaging

If you notice any of these issues, do NOT use the medication. Contact support immediately.


If Your Package Was Delayed or Left in Extreme Temperatures

Concern: Your package sat outside in hot weather (90°F+) or extreme cold (<32°F) for an extended period.

What to do:

  1. Refrigerate the medication immediately

  2. Inspect for visible signs of damage (discoloration, particles, etc.)

  3. Contact support at help.goodgirlrx.com to report the situation

Do NOT use medication if:

  • The vial is cracked or leaking

  • The solution appears discolored or cloudy (if it should be clear)

  • The package shows obvious heat or cold damage

We will evaluate your situation and determine if a replacement is needed.


Storage After Delivery

Once your medication is refrigerated:

  • Keep it in the refrigerator at 36°F to 46°F (2°C to 8°C)

  • Do NOT freeze — Freezing damages most injectable medications

  • Store in original packaging to protect from light

  • Keep away from the freezer compartment — The back of the fridge near the freezer is often too cold

  • Do not store in the door — Temperature fluctuates too much


Multi-Dose Vial Storage

If your medication is a multi-dose vial (used over several weeks):

  • Continue refrigerating between uses

  • Check the included instructions for how long the vial remains usable after first puncture

  • Do not use if past the expiration date or beyond-use date

  • Inspect before each use for any changes in appearance

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